I grew up in the D.C. suburbs, and what I like about that place is that there's not a strong regional affect in the cultural imagination like there is in Dallas or San Francisco or New York City. You have a little more freedom as a novelist this way. The suburbs become a generic idea, and the place doesn't intrude into the narrative.
I always like it when writers posit writing as an act of empathy. It's such a grand turn of phrase, such a noble ideal; empathy is so worth aiming for in life that the same must hold true in art. But personally, I can't think too deeply about that when I'm working, or I'd never get anything down on the page.
In a strange way, Louise Erdrich is perhaps our least famous great American writer; she is not reclusive, but she is reticent, and her public appearances give the impression of a carefully controlled performance. But Erdrich has also shared many of her most intimate emotions and experiences, in some form, in her novels.